Research Profile

Welcome to the webpage of the Chair of Nutritional Physiology.

The Chair was established in 2017 and has been headed by Prof. Dr. Anna Kipp since that time.

We investigate the functions and interactions of essential trace elements, having gained fundamental insights into the interplay between copper and selenium. Furthermore, we aim to understand how deficiencies in selenium, copper, and zinc affect other trace elements and their homeostasis.

However, our most extensive experience lies in the study of the trace element selenium. According to current DGE reference values for nutrient intake, adults should consume 60–70 µg of selenium per day. Yet, a daily intake at this level is rarely achieved in European countries; the status is therefore considered suboptimal. This can negatively impact the immune system or the development of cancer. Our work can be classified as basic research and aims to elucidate mechanistic relationships at the molecular level that can eventually be translated into dietary recommendations. To this end, we utilize human cell lines, feeding studies involving mouse models, and human intervention studies.

Research Focus Areas

  • Investigation of the biochemical and molecular mechanisms of action and interactions of the micronutrient selenium, as well as other trace elements such as copper, zinc, and iron
  • Influence of trace elements and other dietary components on cellular redox regulation
  • Physiology of the healthy intestine and alterations associated with inflammatory bowel disease, colorectal cancer, and liver physiology and pathophysiology
  • Trace element status in aging and sex-dependent regulatory mechanisms